Welcome to prolistem
Novel Solution for Azoospermia
At Prolistem®, we are committed to helping men with azoospermia (zero sperm count) using the latest scientific discoveries. Our patented, FDA-certified formula is designed to support the body in naturally restarting sperm production. Based on advanced research, Prolistem® offers a new hope for men facing fertility challenges. Trust Prolistem® to be your partner on the journey to fatherhood, where science brings real solutions.
Breakthrough Hope for Azoospermia (Men with Zero Sperm Count)
Prolistem® is a patented, all-natural program built for non-obstructive azoospermia (NOA) and backed by real-world clinic use. It holds an FDA Certificate of Free Sale (U.S.) and follows a doctor-informed, step-by-step protocol—not a generic vitamin stack.
How it works (in two phases):
Phase One: Wake Stem cells, a brief, controlled drop in testosterone can activate hidden spermatogonial stem cells.
Phase Two: Rebuild production, testosterone is then restored to support full spermatogenesis over a structured six-month plan.
Why patients and doctors take it seriously:
Patented approach with a clear mechanism—no miracle claims.
Used before micro-TESE to improve the window of success; some men see sperm appear in semen during the program (results vary).
Before starting the Prolistem® program, let’s learn a little more about it.
Learn how to use Prolistem® effectively with clear instructions on dosage, timing, and tips to maximize results
Read real stories of people with maturation arrest or Sertoli cell-only syndrome and their experiences using Prolistem
- Breakthrough Innovation
About Prolistem®
Prolistem® is the result of years of research and innovation, designed to help men with zero sperm count, nil sperm, no sperm, or azoospermia. In the past, men facing these conditions had no way to have children. Today, Prolistem® offers a proven solution to restore fertility and help men start families. With Prolistem®, men with no sperm or zero sperm count can have a chance to become fathers. It’s a new beginning, a fresh hope, and a reason to smile for those battling male infertility.
Prolistem® Fertility Products
FAQ ( Frequently Asked Questions )
Prolistem® was developed specifically for men with non-obstructive azoospermia (primary testicular failure), one of the most challenging forms of male infertility. We’ve seen significant success in many cases, particularly those involving maturation arrest or Sertoli cell-only syndrome with some remaining stem cells.
However, it’s important to understand that azoospermia is a complex condition, and not every case responds the same way. We never promise miracles — what we offer is a scientifically designed protocol that has helped many patients detect sperm where none were found before. In some cases, this has even improved the chances of success with sperm retrieval procedures like microTESE.
Prolistem® can offer real hope — but we are always transparent that it’s not a guaranteed cure for everyone.
Prolistem® is manufactured in an FDA-registered facility in the United States and follows strict quality and safety standards. However, as a dietary supplement, it does not require FDA approval like pharmaceutical drugs do. It is classified under the dietary supplement category, which is regulated differently by the FDA.
We recommend taking Prolistem® for at least 6 months before undergoing procedures like microTESE. In some cases, continued use up to 9–12 months may be beneficial. This gives the body time to complete a full spermatogenic cycle and potentially activate dormant stem cells.
Yes, we’ve seen positive outcomes in some patients who previously had unsuccessful sperm retrieval attempts. Prolistem® may improve the environment for spermatogenesis, increasing the chances of finding sperm in a second procedure — but success is not guaranteed.
Prolistem® is a natural supplement and is generally considered safe. However, as with any supplement, some individuals may be more sensitive than others. That’s why we recommend consulting your doctor before starting Prolistem, especially if you have a medical condition or are taking other medications.
Answer: These genetic conditions are more complex. Some patients with mosaic Klinefelter or partial AZFc deletions may respond, but results vary. A genetic consultation is recommended before starting treatment.
Azoospermia is a challenging condition, and unfortunately, not all patients will respond to treatment. If there is no improvement after completing the Prolistem® protocol, procedures like microTESE may still be considered. In some cases, using Prolistem® beforehand can enhance the chances of finding sperm during surgery by improving the testicular environment.
However, even if no sperm is found during microTESE, we strongly recommend continuing with frequent semen analyses, as recovery and sperm production may occur slowly over time. It’s important to understand that while Prolistem® offers real hope, it is not a guaranteed solution for every case.
To get the best possible results, it’s important to follow our full protocol and instructions, which are available on our website or by scanning the QR code on the product box.
We also recommend not using other treatments or supplements during the Prolistem® course unless specifically approved by your doctor, as combining therapies may interfere with its effectiveness.
OUR NEWS
We are proud to have participated in the 41st Annual ESHRE Conference in Paris, a premier international...
OBJECTIVE To evaluate the efficacy of Prolistem, a novel supplement, in enhancing MicroTESE success rates...
We are honored to participate in the highly anticipated ESHRE 2024 Conference, a global stage where the...
We are honored to participate in the prestigious ASRM 2024 Conference in Denver, Colorado, a cornerstone...
Prolistem® Joins the ASRM 2024 Conference in Denver We are thrilled to announce that Prolistem® will...
The Prolistem treatment has emerged as a breakthrough for men grappling with non-obstructive azoospermia,...
We are thrilled to announce that Prolistem®, developed by Medhija LLC, has received approval from the...
OUR BLOG
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Introduction Male infertility is a significant concern globally, affecting one in six couples trying...
Infertility affects millions of couples worldwide, and in men, one of the more serious diagnoses is azoospermia—a...
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